|
KMID : 0364820090450040312
|
|
Korean Journal of Microbiology
2009 Volume.45 No. 4 p.312 ~ p.317
|
|
|
Structural and Functional Analysis of a Forkhead Gene, fkhF, in a Filamentous Fungus Aspergillus nidulans
|
|
Park Mi-Hye
Han Kap-Hoon
Kim Jong-Hwa
Kim Hyoun-Young
|
|
|
Abstract
|
|
|
|
Genome analysis of a model filamentous fungus, Aspergillus nidulans, revealed that there are six putative forkhead genes. Among them, fkhF (AN8949.2) showed A. nidulans-specific. fkhF gene is located in chromosome VII and composed of 2,337 bp coding region for 778 amino acid. Since little is known about the involvement of the forkhead proteins in the developmental process of the filamentous fungi, including A. nidulans, we generated a deletion mutant of fkhF gene and analyzed. Deletion of fkhF resulted in less-dense conidiophore formation in a solid culture. However, the sexual developmental process or cleistothecia formation was normal. Furthermore, fkhF deletion mutant produced conidiophores and conidia under the submerged culture, suggesting that the fkhF gene is involved in repression of inappropriated induction and maturation of asexual developmental process but not in sexual development.
|
|
|
KEYWORD
|
|
|
A. nidulans, asexual development, forkhead, transcription factor
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|